Saturday, September 12, 2009


Sorry to keep so long with the report on our consult (if anyone was on the edge of their seat ;-) I wasn't home yesterday evening so I couldn't write it up.
Sure, mobile internet connections exist, but I don't have a subscription since they're frightfully expensive here.

The consult went very well. I had given my RE a heads-up of what I wanted to talk about a few weeks ago, and not only had he remembered but he was prepared!
I had a note with my questions, and he had a note with the essentials of my file. Another reason I like this doctor.

The statistics:
About 30 out of 100 of women get PG if they transfer a single embryo in a fresh IVF cycle.
About 40 out of 100 get PG with 2 fresh embryos transferred. Of these 40, on average 1 in 4 will have twins.
I forgot to ask, but I think these are successful pregnancies, with take-home babies.

We talked about complications with twin PG, but I didn't press for statistics. The reason being that my husband and I consider the odds of 1 in 4 rather steep.
Given my age (early thirties), the top quality embryos we had in previous cycle and the fact that we already had a successful PG after IVF, the doctor thinks our odds of having twins would in fact be higher than 1 in 4.

The doctor remarked that FETs don't appear to be our thing, before I even asked, and that he understands the temptation to do a double embryo transfer next time. He would support our decision either way, but generally he would advise doing one more single embryo transfer first. After all, our stats our one successful and one failed SET, which is pretty fabulous.

About FETs, I asked about freezing at day 2 or day 5 in stead.
As I thought, the problem with day 2 is that they can't really tell the quality of each embryo yet, and therefor can't select which would be the top embryo to transfer. Since our best chance is with the fresh transfer, we should make sure we transfer the best one(s).

Day 5 is another option, which they have ample experience with. By day 5, they can really tell which embryos are of the highest quality and straight after transfer the embryo is ready to burrow itself into the womb. The problem is that far less embryos make it to day 5 in vitro. Generally, they propose this option to patients who have 8 good embryos or more on day 3. We had 2 and 3 good embryos on day 3 in our respective IVF cycles. We could ask to attempt a day 5 transfer anyway, but unless we were to have significantly more good embryos on day 3, I'm not keen to take the risk. Having nothing to transfer after all the effort is pretty depressing.

In conclusion, we're doing one more single embryo transfer (if given the chance, knock on wood). After that, it's double or nothing!
If next time there are only medium quality embryos, we transfer two. I didn't ask about transferring one good and one medium (not-freezing quality). I'll ask that at the next blood draw or u/s.

So, I've been swayed, not because transferring two would be a wrong decision, it just isn't right for us. Not yet.

Thanks for your support and helpful suggestions. We didn't discuss changing the protocol, perhaps we should have.
A vitamin boost for my husband can never hurt (or me), but aren't we too late to improve semen quality? It takes about 2 months to make them, if memory serves, and I hope our retrieval will be at the end of Octobre. Hm, maybe still just in time. I'll have to make smoothies every day though (yum!), my husband never eats fruit on his own (feel free to roll your eyes). And then there's his smoking ... (strictly outside and against my known disapproval).

Thanks for the comments and tips! Next step is picking up my meds at the clinic. Baseline u/s is scheduled for mid Octobre.


At 12 September, 2009 22:02, Blogger lucky #2 said...

Early 30s...I'd totally stick with that single embryo transfer for another round. While twins sound so "romantic" to finish the IF hell, multiples are HARD, HARD work (and risky as you know).

Sounds like a fabulous plan & one I would be able to sleep knowing was in place. Glad to hear from you !:)

At 12 September, 2009 23:53, Anonymous Anonymous said...

I think your decision is sound.

At 13 September, 2009 22:38, Blogger Thalia said...

Think you are on the right track.

At 15 September, 2009 06:22, Blogger Sparkle said...

Sounds like a good appointment. Helps to make the right decisions :-)

At 17 September, 2009 08:42, Anonymous Jys said...

All sounds so interesting and educational! And best of all, looks like the chances are great and you have an exciting time ahead of you! Seriously, even though we complain so hard about how hard it is (which is certainly NOT easy), at least one side benefit is also how exciting and AMAZING it all is.
Sounds like you also have a really great RE - understanding, giving great personal attention, and knowlegeable. I can't wait to hear how things progress!


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